BLACK Lives Matter protesters blocked a street outside a Brisbane court today, following an earlier arrest at a rally through the CBD.

Garrick St, outside the Brisbane Arrest Court, was blocked by activists sitting on the road chanting "always was, always will be aboriginal land".

The protesters had earlier gathered in King George Square before marching down Albert St and on to State Parliament.

It is believed that the activists then responded to a social media request to move to the Roma Street Watchhouse, following the arrest of a prominent Indigenous campaigner.

Dozens of police officers lined up in front of the group.

Protesters at times became aggressive, with one woman standing inches from a police woman's face, screaming at her.

Another person repeatedly screamed at officers "take your f**king gun off c**ts.

Police did not react to the aggression, standing quietly.

One protester shouted on a megaphone demanding "someone in charge" come and talk with the group, saying he wanted to talk to the Premier, Police Minister or Police Commissioner.

"This is gonna be a stand-off," he said.

"We're not moving until someone comes here of authority.

"We don't deal with threats, we don't deal with violence."

The protesters were later dispersed.

Earlier, more than 100 protesters were spotted moving through King George Square, in defiance of social distancing restrictions.

Extra police were on the scene.